((4-Hydroxybutyl)Azanediyl)Bis (Hexane-6,1-Diyl)Bis (2-Hexyldecanoate)
Цена: 46000 руб.
Минимальный заказ: 1 шт.
Product Name: ((4-hydroxybutyl)azanediyl)bis (hexane-6,1-diyl)bis (2-hexyldecanoate)
Synonyms: ALC-0315; Lipid ALC-0315; ((4-hydroxybutyl)azanediyl)bis (hexane-6,1-diyl) bis (2-hexyldecanoate); 6-[6-(2-hexyldecanoyloxy)hexyl-(4-hydroxybutyl)amino]hexyl 2-hexyldecanoate; Decanoic acid, 2-hexyl-, 1,1-[[(4-hydroxybutyl)imino]di-6,1-hexanediyl] ester; Decanoic acid, 2-hexyl-, 1,1′-[[(4-hydroxybutyl)imino]di-6,1-hexanediyl] ester
Molecular Formula: C48H95NO5
Molecular Weight: 766.272
Cationic liposome ((4-hydroxybutyl)azanediyl)bis (hexane-6,1-diyl)bis (2-hexyldecanoate), also known as: ALC-0315, which is a synthetic cationic lipid (or ionizable lipid). As a PEGylated lipid, it is a colourless oily substance.
At physiological pH, ALC-0315 is protonated at the nitrogen atom to produce ammonium cations, which are attracted to messenger RNA (mRNA) (messenger RNA is anionic). This property enables cationic liposomes to bind to drugs, genes and other bioactive substances to form positively charged complexes, which help these molecules cross the cell membrane and enter the cell. Therefore, ALC-0315 is often used in the delivery of nucleic acid drugs (including mRNA vaccines, etc.).
Бренд: Handom Chemicals
Страна: China
Вес: 0.001 кг
Appearance: Colourless to yellowish liquid
Identification (H-NMR): Complies with the reference substance structure
Identification (IR): Complies with the reference substance structure
Identification (Molecular Weight): Complies
Assay: 90.0% ~ 110.0%
Purity: Not less than 90.0%
Impurities (DHA Impurity-1): Not more than 1.00%
Impurities (DHA Impurity-2): Not more than 1.00%
Impurities (DHA Impurity-3): Not more than 1.00%
Impurities (DHA Impurity-5): Not more than 1.00%
Impurities (DHA Impurity-7): Not more than 1.00%
Residual Solvents (Dichloromethane): Not more than 600 ppm
Residual Solvents (n-Hexane): Not more than 290 ppm
Residual Solvents (Methanol): Not more than 3000 ppm
Residual Solvents (n-Heptane): Not more than 5000 ppm
Residual Solvents (Ethyl Acetate): Not more than 5000 ppm
Residual Solvents (Acetonitrile): Not more than 410 ppm
Moisture: Not more than 1.00%
Bacterial Endotoxin: Not more than 0.1 EU/mg
Total Aerobic Microbial Count: Not more than 100 CFU/g
Total combined Yeasts & Mold Count: Not more than 10 CFU/g
Elemental Impurities (Copper): Not more than 30 ppm
Elemental Impurities (Arsenic): Not more than 1.5 ppm
Elemental Impurities (Cadmium): Not more than 0.2 ppm
Elemental Impurities (Mercury): Not more than 0.3 ppm
Elemental Impurities (Lead): Not more than 0.5 ppm
Elemental Impurities (Cobalt): Not more than 0.5 ppm
Elemental Impurities (Vanadium): Not more than 1.0 ppm
Elemental Impurities (Nickel): Not more than 2.0 ppm
Elemental Impurities (Lithium): Not more than 25 ppm
Elemental Impurities (Antimony): Not more than 9 ppm
Чтобы купить ((4-Hydroxybutyl)Azanediyl)Bis (Hexane-6,1-Diyl)Bis (2-Hexyldecanoate) оптом по цене 46000 руб., свяжитесь с поставщиком. Компания поставщик — Handom Chemicals из города Далянь (Liaoning). Минимальная партия 1 шт. Доставка возможна транспортной компанией, авиатранспортом, железной дорогой, курьером. Способы оплаты: безналичная оплата, электронные деньги, кредитные карты.
